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Zygomycosis (Mucormycosis)

Introduction
Zygomycosis is the broadest term to refer to infections caused by bread mold fungi of the zygomycota phylum. Mucormycosis (zygomycosis) is a serious, potentially deadly fungal infection that's infrequently diagnosed.
Causes
Many different fungi may cause mucormycosis; infections with the Mucoraceae family of fungi predominate as causes; hence, many investigators use the term mucormycosis instead of zygomycosis.
Symptoms
Most of the symptoms of mucormycosis do not differ to any major extent between the various fungal causes. Most common symptoms include fever, headache, reddish and swollen skin over nose and sinuses, dark scabbing in the nose by the eye(s), visual problems, eye(s) swelling, facial pain
Diagnosis
Diagnosis requires deep skin biopsy from the subcutaneous mass for histopathology and for microscopy and fungal culture.
Treatment
Treatment is difficult and prolonged for both types of Zygomycosis and the results for Conidiobolus are particularly disappointing.
Therapies may include:
  • Itraconozole
  • Fluconozole
  • Amphotericin B
  • Voriconazole

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