The goal of any oral thrush treatment is to stop the rapid spread of the fungus, but the best approach may depend on your age, your overall health and the cause of the infection.
Healthy adults and children
If an adult patient is diagnosed with a mild case of thrush, the doctor may prescribe an antifungal mouthwash (nystatin) or lozenges (clotrimazole [Mycelex]) for short-term use. Miconazole buccal (Oravig) is an antifungal medication that consists of a tablet placed in the upper gum region and dissolved in the mouth to get rid of thrush.
Infants and children
Infants, toddlers, and children with thrush often do not require treatment. In children who have thrush for more than a few weeks, a child's pediatrician may prescribe antifungal nystatin (Mycostatin, Nilstat, Nystex) drops.
Adults with weak immune systems
For more severe cases of thrush or if someone has other reasons for a weakened immune system, he or she may need stronger systemic medications, such as fluconazole (Diflucan) or itraconazole (Sporanox). These medications usually work better than ketoconazole (Nizoral). For severe or resistant thrush, amphotericin B may be prescribed.